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Products Details
Product Description
– PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains[1][2].
Web ID
– HY-103250
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C44H65N5O10
References
– [1]Zientek M, et al. In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase. Drug Metab Dispos. 2010;38(8):1322-1327.|[2]Magee TV, et al. Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections. J Med Chem. 2009;52(23):7446-7457.
CAS Number
– 893556-85-9
Molecular Weight
– 824.01
SMILES
– O=C1N(C2CN([C@@H](C3=CC=NC4=C3C=CC=N4)C)C2)[C@@]([C@H]5C)([H])[C@@](C)([C@H](OC([C@@H](C([C@H](C)[C@@H](O[C@@]6([H])[C@@H]([C@H](C[C@@H](C)O6)N(C)C)O)[C@@](OC)(C)C[C@@H](C)C5=O)=O)C)=O)CC)O1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic
Isoform
– Macrolide
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
