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PF-1355
SKU
HY-100873-10 mg
Category Reference compound
Tags Cardiovascular Disease, Glutathione Peroxidase, Metabolic Enzyme/Protease
$90 – $650
Products Details
Product Description
– PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor, used for treatment of vasculitic diseases.
Web ID
– HY-100873
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H15N3O4S
References
– [1]Zheng W, et al. PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti-glomerular basement membrane glomerulonephritis. J Pharmacol Exp Ther. 2015 May;353(2):288-98
CAS Number
– 1435467-38-1
Molecular Weight
– 321.35
Compound Purity
– 99.86
SMILES
– O=C(N)CN(C(N1)=S)C(C2=CC(OC)=CC=C2OC)=CC1=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Glutathione Peroxidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.