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PF-1355

$90$650

Products Details

Product Description

– PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor, used for treatment of vasculitic diseases.

Web ID

– HY-100873

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C14H15N3O4S

References

– [1]Zheng W, et al. PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti-glomerular basement membrane glomerulonephritis. J Pharmacol Exp Ther. 2015 May;353(2):288-98

CAS Number

– 1435467-38-1

Molecular Weight

– 321.35

Compound Purity

– 99.86

SMILES

– O=C(N)CN(C(N1)=S)C(C2=CC(OC)=CC=C2OC)=CC1=O

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– DMSO : 50 mg/mL (ultrasonic)

Target

– Glutathione Peroxidase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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