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Products Details
Product Description
– PF-06795071 is a potent and selective covalent MAGL inhibitor with an IC50 of 3 nM[1].
Web ID
– HY-111512
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H17F4N3O3
References
– [1]McAllister LA, et al. Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. J Med Chem. 2018 Apr 12;61(7):3008-3026.
CAS Number
– 2075629-81-9
Molecular Weight
– 399.34
SMILES
– OC[C@H](C(F)(F)F)OC(N1C[C@]([C@@]2([H])C1)([H])[C@H]2C3=NN(C4=CC=C(F)C=C4)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– MAGL
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
