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PF-06478939 (TFA)
SKU
HY-153964A-Get quote
Category Reference compound
Tags Cardiovascular Disease, GPCR/G Protein, Oxytocin Receptor
Products Details
Product Description
– PF-06478939 TFA is a non-brain-penetrating peptide that is an agonist at oxytocin (OT) receptor and vasopressin receptor with EC50 values of 0.01 nM and 0.078 nM, respectively[1].
Web ID
– HY-153964A
Shipping
– Room temperature
Molecular Formula
– C78H134N14O22S2.xC2HF3O2
References
– [1]Modi ME, et al. Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing. J Pharmacol Exp Ther. 2016 Aug;358(2):164-72.
Molecular Weight
– N/A
SMILES
– OC1=CC=C(C[C@@H](C(N[C@@H]([C@H](CC)C)C(N[C@H](C(N[C@H]2CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](N)CSSC[C@@H](C(N3CCC[C@H]3C(N[C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCCCCCCCCCCCC)=O)=O)C(NCC(N)=O)=O)=O)=O)NC2=O)=O)C=C1.O=C(O)C(F)(F)F.[x]
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Oxytocin Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
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