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Products Details
Product Description
– PF-06371900 is a potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor[1].
Web ID
– HY-134562
Shipping
– Room temperature
Molecular Formula
– C17H16N6O2S
References
– [1]Henderson JL, et al. Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32.
CAS Number
– 1622291-81-9
Molecular Weight
– 368.41
SMILES
– CN1N=CC(C2=NN=C3C=CC(SC4=CC(OC)=CC=C4OC)=NN32)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– LRRK2
Pathway
– Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
