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PF-04745637
$142 – $450
Products Details
Product Description
– PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1[1].
Web ID
– HY-120689
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H32ClF3N2O2
References
– [1]Laurie B. Schenkel, et al. The discovery of a potent series of carboxamide TRPA1 antagonists. J. Med. Chem. 2016, 59, 6, 2794-2809.
CAS Number
– 1917294-46-2
Molecular Weight
– 509.00
Compound Purity
– 98.65
SMILES
– O=C(C1(C2=CC=C(Cl)C=C2)CCCC1)NCC(N3CCC(C(F)(F)F)(O)CC3)CC4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– TRP Channel
Isoform
– TRPA
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
