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Products Details
Product Description
– PEX5-PEX14 PPI-IN-2 (compound 12) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor. PEX5-PEX14 PPI-IN-2 inhibits PEX14-PEX5 PPI with EC50 values of 5 and 17 µM in T. b. brucei and HepG2 cells, respectively. PEX5-PEX14 PPI-IN-2 can be used in the research of diseases related to trypanosome infection[1].
Web ID
– HY-155531
Shipping
– Room temperature
Molecular Formula
– C25H26N4O3
References
– [1]Marciniak M, et al. Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template. Eur J Med Chem. 2023 Oct 5;258:115587.
Molecular Weight
– 430.50
SMILES
– O=C(OC)[C@@H](N1C[C@H](CC2=CNC3=C2C=CC=C3)NC(C1)=O)CC4=CNC5=C4C=CC=C5
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Biochemical Assay Reagents
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
