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Perindoprilat
$80 – $300
Products Details
Product Description
– Perindoprilat (S 9780) is an angiotensin-converting enzyme (ACE) inhibitor with the IC50 value ranging from 1.5 to 3.2 nM. Perindoprilat can be used in hypertension research[1][2].
Web ID
– HY-B1433
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C17H28N2O5
References
– [1]Perindopril. Expert Opin Pharmacother. 2006 Jan;7(1):63-71.|[2]Angiotensin-converting enzyme (ACE) inhibitors have different selectivity for bradykinin binding sites of human somatic ACE. Eur J Pharmacol. 2007 Dec 22;577(1-3):1-6.|[3]X-Z Wang, et al. Perindopril inhibits myocardial apoptosis in mice with acute myocardial infarction through TLR4/NF-κB pathway. Eur Rev Med Pharmacol Sci. 2019 Aug;23(15):6672-6682.|[4]Izabella Z A Pawluczyk, et al. The role of bradykinin in the antifibrotic actions of perindoprilat on human mesangial cells. Kidney Int. 2004 Apr;65(4):1240-51.
CAS Number
– 95153-31-4
Molecular Weight
– 340.41
Compound Purity
– 99.53
SMILES
– O=C([C@H]1N(C([C@@H](N[C@H](C(O)=O)CCC)C)=O)[C@@]2([H])CCCC[C@@]2([H])C1)O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)|H2O : 250 mg/mL (ultrasonic)
Target
– Angiotensin-converting Enzyme (ACE)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
