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Peramivir (trihydrate)
$80 – $560
Products Details
Product Description
– Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes[1][2].
Web ID
– HY-17015
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C15H34N4O7
Citations
– Antimicrob Agents Chemother. 2020 Jun 23;64(7):e00222-20.|PLoS One. 2018 Jul 12;13(7):e0200761. |Chemosphere. 2017 Feb;169:550-557.|Int Immunopharmacol. 2023 Jan 11;115:109706.|Nat Commun. 2013;4:2854.|PLoS One. 2015 Jun 25;10(6):e0131412.|Sci Rep. 2021 Aug 11;11(1):16293.|University of Glasgow. School of Cancer Sciences.
References
– [1]Babu YS, et al. BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design. J Med Chem. 2000 Sep 21;43(19):3482-6.|[2]Young D, et al. RWJ-270201 (BCX-1812): a novel neuraminidase inhibitor for influenza. Philos Trans R Soc Lond B Biol Sci. 2001 Dec 29;356(1416):1905-13.
CAS Number
– 1041434-82-5
Molecular Weight
– 382.45
Compound Purity
– 99.53
SMILES
– O[C@H]1[C@]([C@H](C(CC)CC)NC(C)=O)([H])[C@H](NC(N)=N)C[C@@H]1C(O)=O.[H]O.[H]O.[H]O
Clinical Information
– Launched
Research Area
– Infection
Solubility
– DMSO : < 1 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic)
Target
– Influenza Virus
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
