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Products Details
Product Description
– Pencitabine (Pen) is an orally active anticancer agent. Pencitabine interferes with DNA synthesis and function by inhibiting multiple nucleotide-metabolizing enzymes and by misincorporation into DNA[1].
Web ID
– HY-145705
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H20F3N3O6
References
– [1]Kalman TI. Rational Design of an Orally Active Anticancer Fluoropyrimidine, Pencitabine, a Hybrid of Capecitabine and Gemcitabine. ACS Med Chem Lett. 2022 Feb 21;13(3):409-416.
CAS Number
– 2249843-29-4
Molecular Weight
– 395.33
SMILES
– FC1([C@H](N2C(N=C(C(F)=C2)NC(OCCCCC)=O)=O)O[C@@H]([C@H]1O)CO)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
