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Products Details
Product Description
– PEG40K unconjugated/naked AX102 sodium is a DNA oligonucleotide aptamer for platelet-derived growth factor PDGF-B. PEG40K unconjugated/naked AX102 sodium is AX102 without PEG40K conjugation. AX102 is 34 bases in length, selectively binds platelet-derived growth factor B (PDGF-B), and causes tumor vessel regression[1].
Web ID
– HY-160048
Shipping
– Room temperature
Molecular Formula
– N/A
References
– [1]Sennino B, Falcón BL, McCauley D, Le T, McCauley T, Kurz JC, Haskell A, Epstein DM, McDonald DM. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res. 2007 Aug 1;67(15):7358-67.
Molecular Weight
– N/A
SMILES
– [PEG40K unconjugated/naked AX102 (sodium)]
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Platelet-derived Growth Factor (PDGF)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
