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Pectolinarin
$50 – $140
Products Details
Product Description
– Pectolinarin possesses anti-inflammatory activity[1]. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway[2].
Web ID
– HY-N0314
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C29H34O15
References
– [1]Lim H, et al. Anti-inflammatory activity of pectolinarigenin and pectolinarin isolated from <i>Cirsium chanroenicum</i>. Biol Pharm Bull. 2008 Nov;31(11):2063-7.|[2]Wang L, et al. Pectolinarin inhibits proliferation, induces apoptosis, and suppresses inflammation in rheumatoid arthritis fibroblast-like synoviocytes by inactivating the phosphatidylinositol 3 kinase/protein kinase B pathway.J Cell Biochem. 2019 Sep;120(9):15202-15210.
CAS Number
– 28978-02-1
Molecular Weight
– 622.57
Compound Purity
– 99.89
SMILES
– O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]5[C@@H]([C@@H]([C@H]([C@H](C)O5)O)O)O)O4)O)O)O)=C(OC)C(O)=C13
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 31.25 mg/mL (ultrasonic)
Target
– Apoptosis;Interleukin Related;Prostaglandin Receptor
Isoform
– EP;IL-6;IL-8
Pathway
– Apoptosis;GPCR/G Protein;Immunology/Inflammation
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
