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PDMP (hydrochloride)
$83 – $132
Products Details
Product Description
– PDMP hydrochloride is a glucosylceramide synthase (GCS) inhibitor. PDMP hydrochloride induces apoptosis in K562/A02 cells. PDMP hydrochloride can be used in cancer (such as leukemia) research[1][2].
Web ID
– HY-116392D
Shipping
– Room temperature
Molecular Formula
– C23H38lN2O3.xHCl
References
– [1]Yin L, et al. Effect of PDMP, a glucosylceramide synthase inhibitor, on reversion of daunorubicin resistance in human leukemia cell line K562/A02. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Feb;18(1):79-84.|[2]Casson L, et al. Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins. PLoS One. 2013;8(1):e54525.
CAS Number
– 73257-80-4
Molecular Weight
– N/A
SMILES
– CCCCCCCCCC(NC(CN1CCOCC1)C(C2=CC=CC=C2)O)=O.[x].Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Glucosylceramide Synthase (GCS)
Pathway
– Apoptosis;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
