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Products Details
Product Description
– PDE5-IN-11 is a potent inhibitor of PDE5 with an IC50 of 40 nM. PDE5-IN-11 also inhibits PDE4 and PDE6 with IC50s of 1.78 and 0.09 μM, respectively[1].
Web ID
– HY-149661
Shipping
– Room temperature
Molecular Formula
– C20H28N6O4
References
– [1]Jiayuan Liu, et al. Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors, European Journal of Medicinal Chemistry (2023).
Molecular Weight
– 416.47
SMILES
– COC1=CC=C(CNC2=C3C(N(C(C)C)C(N3)=O)=NC(N(CCO)CCO)=N2)C=C1
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
