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Products Details
Product Description
– PDE4-IN-3 is a novel and orally active PDE4 inhibitor with potent inhibitory affinity (IC50 = 4.2 nM).
Web ID
– HY-132887
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C35H33FO8
References
– [1]Huang YY, et al. Mangostanin Derivatives as Novel and Orally Active Phosphodiesterase 4 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis with Improved Safety. J Med Chem. 2021 Sep 23;64(18):13736-13751.
CAS Number
– 2755687-49-9
Molecular Weight
– 600.63
SMILES
– O=C1C2=C(OC3=CC(OCC4=CC=C(C=C4)F)=C(C(C/C=C(C)C)=C31)OC)C=C5OC(C)(C=CC5=C2OC/C=C/C(O)=O)C
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Isoform
– PDE4
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
