Products Details

Product Description

– PD24 is an AChE and BuChE inhibitor (hAChE IC50: 1.72 μM; eeAChE IC50: 1.76 μM; eqBuChE IC50: 2.64 μM). PD24 also has antioxidant activity, and inhibits DPPH (IC50: 28.72 μM). PD24 can be used for research of Alzheimer’s disease[1].

Web ID

– HY-155621

Shipping

– Room temperature

Molecular Formula

– C24H22N2O6

References

– [1]Bhanukiran K, et al. Discovery of Multitarget-Directed Ligands from Piperidine Alkaloid Piperine as a Cap Group for the Management of Alzheimer’s Disease. ACS Chem Neurosci. 2023 Aug 2;14(15):2743-2760.

Molecular Weight

– 434.44

SMILES

– O=C(N1CCN(C(C2=CC=C(OCO3)C3=C2)=O)CC1)/C=C/C=C/C4=CC=C(OCO5)C5=C4

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE)

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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