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Products Details
Product Description
– PD-334581 is a MEK1 inhibitor[1].
Web ID
– HY-107619
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H19F3IN5O2
References
– [1]Ohren JF, et al. Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. Nat Struct Mol Biol. 2004 Dec;11(12):1192-7.
CAS Number
– 548756-68-9
Molecular Weight
– 545.30
SMILES
– FC1=C(F)C(NC2=CC=C(C=C2F)I)=C(C3=NN=C(NCCN4CCOCC4)O3)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MEK
Isoform
– MEK1
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
