Products Details

Product Description

– PD-159020 is a non-selective ETA/ETB antagonist, with IC50s of 30 and 50 nM for hETA and hETB, respectively.

Web ID

– HY-101598

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C32H25NO8

References

– [1]Amy Mbunker, et al. 1,3-diaryl-2-carboxyindoles as potent non-peptide endothelin antagonists. Bioorganic & Medicinal Chemistry Letters. Volume 6, Issue 9, 7 May 1996, Pages 1061-1066

CAS Number

– 177904-00-6

Molecular Weight

– 551.54

SMILES

– O=C(C(N1CC2=CC=C(OCO3)C3=C2)=C(C4=CC=C(OCO5)C5=C4)C6=C1C=C(OCC7=CC=CC=C7)C(OC)=C6)O

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease; Endocrinology

Solubility

– 10 mM in DMSO

Target

– Endothelin Receptor

Isoform

– ETA;ETB

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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