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PD-156707
SKU
HY-123744-Get quote
Category Reference compound
Tags Cardiovascular Disease, Endothelin Receptor, GPCR/G Protein
Products Details
Product Description
– PD-156707 is an orally active, nonpeptide and selective Endothelin-A receptor antagonist[1].
Web ID
– HY-123744
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C28H25NaO9
References
– [1]Andrew C. G. Uprichard, et al. PD- 156707: A Selective Endothelin-A Receptor Antagonist. Cardiovascular Drug Reviews Vol. 16, No. 2, pp. 89-104.|[2]D P Ignasiak, et al. Effects of endothelin ETA receptor antagonism with PD 156707 on hemodynamics and renal vascular resistance in rabbits. Eur J Pharmacol. 1997 Mar 5;321(3):295-300.
CAS Number
– 162412-70-6
Molecular Weight
– 528.48
SMILES
– O=C(/C(C1=CC=C2OCOC2=C1)=C(C(C3=CC=C(C=C3)OC)=O)/CC4=CC(OC)=C(C(OC)=C4)OC)O[Na]
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Endothelin Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.