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PD 132002
SKU
HY-129695-Get quote
Category Reference compound
Tags Cardiovascular Disease, Metabolic Enzyme/Protease, Renin
Products Details
Product Description
– PD 132002 is an orally active, potent renin inhibitor. PD 132002 weakly inhibits pepsin. PD 132002 produces substantial reductions in blood pressure[1].
Web ID
– HY-129695
Shipping
– Room temperature
Molecular Formula
– C31H50N4O9S
References
– [1]J T Repine, et al. Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate. J Med Chem. 1991 Jul;34(7):1935-43.
CAS Number
– 134452-04-3
Molecular Weight
– 654.82
SMILES
– O=C(C(NC([C@@H](NS(=O)(N1CCOCC1)=O)CC2=CC=CC=C2)=O)C(OC)=O)N[C@H]([C@@H](O)[C@@H](O)CC(C)C)CC3CCCCC3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Renin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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