Download Files:
Products Details
Product Description
– PD 119819 is a highly selective benzopyran-4-one brain dopamine autoreceptor agonist. PD 119819, a heterocyclic piperazine, inhibits spontaneous locomotor activity and brain dopamine synthesis[1][2].
Web ID
– HY-118402
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H25Cl2N3O3
References
– [1]Macallum GE, et al. Renal and hepatic toxicity of a benzopyran-4-one in the Cynomolgus monkey. Toxicology. 1989;59(1):97-108.|[2]Jaen JC, et al. Dopamine autoreceptor agonists as potential antipsychotics. 2. (Aminoalkoxy)-4H-1-benzopyran-4-ones. J Med Chem. 1991;34(1):248-256.
CAS Number
– 105277-43-8
Molecular Weight
– 438.35
SMILES
– O=C1C=COC2=CC(OCCCN3CCN(CC3)C4=NC=CC=C4)=CC=C12.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Isoform
– Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
