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Products Details
Product Description
– PD-1/PD-L1-IN 5 TFA is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].
Web ID
– HY-129172
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H18N4O3S.xC2HF3O2
References
– [1]Kaijiong Xiao, et al. Heterocyclic compounds as immunomodulators. WO2017222976A1.
CAS Number
– 2170209-52-4
Molecular Weight
– N/A
SMILES
– N#CC1=C(NC(C2=NC3=C(CNCC3)S2)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4.OC(C(F)(F)F)=O.[x]
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PD-1/PD-L1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
