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Products Details
Product Description
– PD-1/PD-L1-IN-25 (compound D2) is an inhibitor of PD-1/PD-L1 interaction with an IC50 value of 16.17 nM. PD-1/PD-L1-IN-25 activates the antitumor immunity of T cells efficiently in PBMCs. PD-1/PD-L1-IN-25 can be used for the research of cancer[1].
Web ID
– HY-143305
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H24ClN3O5
References
– [1]Lu L, et al. Design, Synthesis, and Evaluation of PD-1/PD-L1 Antagonists Bearing a Benzamide Scaffold. ACS Med Chem Lett. 2022 Mar 29;13(4):586-592.
CAS Number
– 2768759-52-8
Molecular Weight
– 493.94
SMILES
– O=C(C1=C(C(C2=CC3=C(OCCO3)C=C2)=CC=C1)Cl)NC4=NC=C(C=C4)CN5CC[C@@H](C5)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PD-1/PD-L1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
