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Products Details
Product Description
– PD-1/PD-L1-IN-22 (Example 2) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-22 blocks PD-1/PD-L1 with the IC50 of 0.732 μM. PD-1/PD-L1-IN-22 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
Web ID
– HY-145773
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H26BrClN2O3
References
– [1]Phenylate derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202276A1.
CAS Number
– 2159063-12-2
Molecular Weight
– 517.84
SMILES
– O=C(C)NCCNCC1=CC(Cl)=C(C=C1OC)OCC2=CC=CC(C3=CC=CC=C3)=C2Br
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PD-1/PD-L1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
