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Products Details
Product Description
– PCSK9 ligand 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) ligand. PCSK9 ligand 1 does not affect PCSK9 function[1].
Web ID
– HY-141724
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C34H34FN3O6S
References
– [1]Whitney L Petrilli, et al. From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9. Cell Chem Biol. 2020 Jan 16;27(1):32-40.e3.
CAS Number
– 2215931-60-3
Molecular Weight
– 631.71
SMILES
– O=C(NC1=NC=CS1)C[C@@]2(C3=CC(OC4=CC(F)=C(C5=CC=C(C=C5)C(O)=O)C=C4)=C(OCC6CCCCO6)C=C3CCN2)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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