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Products Details
Product Description
– PCSK9-IN-20 (Compound 3i) is a PCSK9 inhibitor with an IC50 of 3.96 µM. PCSK9-IN-20 decreases PCSK9 and increases LDLR protein expression in vitro[1].
Web ID
– HY-155415
Shipping
– Room temperature
Molecular Formula
– C27H32N6O5S2
References
– [1]Zhixin Ma, et al. Identification of benzothiazoles as novel PCSK9 inhibitors. Bioorg Med Chem Lett. 2023 Nov 6:129542.
CAS Number
– 2929219-77-0
Molecular Weight
– 584.71
SMILES
– O=S(C1=CC=C(C(NC2=NC3=CC=C(CN4CCN(C(OC(C)(C)C)=O)CC4)C=C3S2)=O)C=C1)(NCCC#N)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
