Download Files:
Products Details
Product Description
– PCSK9-IN-19 (Compound 1) is a PCSK9 inhibitor. PCSK9-IN-19 can be used for research of high LDL-cholesterol levels and prevention of coronary artery disease[1].
Web ID
– HY-155006
Shipping
– Room temperature
Molecular Formula
– C81H105ClFN15O15S2
References
– [1]Kuethe JT, et al. Synthesis of a Complex and Highly Potent PCSK9 Inhibitor. Org Lett. 2023 Jul 14;25(27):5001-5005.
Molecular Weight
– 1647.37
SMILES
– C[N+](CCOCCOCCC(NC[C@H](NC(CCSCC1=CC(CSCCNC2=O)=CC3=C1)=O)C(N[C@H](C)C(N[C@H](C(N[C@@H]4CC5=CN(CC6=CN3N=N6)C7=C5C=C(F)C=C7)=O)CC8=CC(C/C=C/CO[C@H]([C@@]9([H])C(N[C@H](C(N[C@H](C(N%10CCC[C@]%102C)=O)CC%11=CC=C(OC)C=C%11)=O)[C@H](O)C)=O)CC[N@@]9C4=O)=CC=C8)=O)=O)=O)(C)C.[Cl-]
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
