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PCSK9-IN-19

Products Details

Product Description

– PCSK9-IN-19 (Compound 1) is a PCSK9 inhibitor. PCSK9-IN-19 can be used for research of high LDL-cholesterol levels and prevention of coronary artery disease[1].

Web ID

– HY-155006

Shipping

– Room temperature

Molecular Formula

– C81H105ClFN15O15S2

References

– [1]Kuethe JT, et al. Synthesis of a Complex and Highly Potent PCSK9 Inhibitor. Org Lett. 2023 Jul 14;25(27):5001-5005.

Molecular Weight

– 1647.37

SMILES

– C[N+](CCOCCOCCC(NC[C@H](NC(CCSCC1=CC(CSCCNC2=O)=CC3=C1)=O)C(N[C@H](C)C(N[C@H](C(N[C@@H]4CC5=CN(CC6=CN3N=N6)C7=C5C=C(F)C=C7)=O)CC8=CC(C/C=C/CO[C@H]([C@@]9([H])C(N[C@H](C(N[C@H](C(N%10CCC[C@]%102C)=O)CC%11=CC=C(OC)C=C%11)=O)[C@H](O)C)=O)CC[N@@]9C4=O)=CC=C8)=O)=O)=O)(C)C.[Cl-]

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Ser/Thr Protease

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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