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Products Details
Product Description
– PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Web ID
– HY-138756
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C47H55N5O16
References
– [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.
CAS Number
– 2055025-02-8
Molecular Weight
– 945.96
SMILES
– [O-][N+](C(C(C(OC(ON1C(CCC1=O)=O)=O)C)=C2)=CC(OCCCC(NCCOCCOCCOCCOCCC(NCCC(N3CC4=C(C=CC=C4)C#CC5=C3C=CC=C5)=O)=O)=O)=C2OC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PROTAC Linkers
Isoform
– PEG Linkers
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
