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PARP-1-IN-4
$50 – $260
Products Details
Product Description
– PARP-1-IN-4 is a PARP-1 inhibitor. PARP-1-IN-4 has inhibitory activity against PARP-1 with IC50 value of 302 μM. PARP-1-IN-4 can be used for the research of lung adenocarcinoma[1].
Web ID
– HY-153590
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C22H15Cl2N3O2
References
– [1]Almahli H, et al. Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer. Bioorg Chem. 2018;77:443-456.
CAS Number
– 684234-56-8
Molecular Weight
– 424.28
Compound Purity
– 99.74
SMILES
– O=C(CN1N=C(C2=C(C1=O)C=CC=C2)C3=CC=C(Cl)C=C3)NC4=CC=C(C=C4)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 7.69 mg/mL (ultrasonic;warming;adjust pH to 2 with HCl;heat to 60°C)
Target
– PARP
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
