![](https://immunomart.com/wp-content/uploads/2024/03/HY-14958.gif)
Download Files:
Pardoprunox
SKU
HY-14958-Get quote
Category Reference compound
Tags 5-HT Receptor;Adrenergic Receptor;Dopamine Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease; Endocrinology
Products Details
Product Description
– Pardoprunox (SLV-308) is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively[1].
Web ID
– HY-14958
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C12H15N3O2
References
– [1]Glennon JC, et al. In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist. Synapse. 2006 Dec 15;60(8):599-608.|[2]Bronzova J, et al. Double-blind study of pardoprunox, a new partial dopamine agonist, in early Parkinson’s disease. Mov Disord. 2010 Apr 30;25(6):738-46.|[3]Bétry C, et al. In vivo effects of pardoprunox (SLV308), a partial D?/D? receptor and 5-HT1A receptor agonist, on rat dopamine and serotonin neuronal activity. Synapse. 2011 Oct;65(10):1042-51.
CAS Number
– 269718-84-5
Molecular Weight
– 233.27
SMILES
– O=C1OC2=C(N3CCN(C)CC3)C=CC=C2N1
Clinical Information
– Phase 3
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Adrenergic Receptor;Dopamine Receptor
Isoform
– 5-HT1 Receptor;D2 Receptor;D3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.