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PAPA NONOate
SKU
HY-134636-10 mg
Category Reference compound
Tags Endocrinology, Endogenous Metabolite, Metabolic Enzyme/Protease
$50 – $250
Products Details
Product Description
– PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site[1][2][3].
Web ID
– HY-134636
Storage Temperature
– -80°C, sealed storage, away from moisture and light
Shipping
– Dry Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C6H16N4O2
References
– [1]Rössig L, et al. Nitric oxide inhibits caspase-3 by S-nitrosation in vivo. J Biol Chem. 1999 Mar 12;274(11):6823-6.|[2]N Dashti, et al. Study of the effect of PAPA NONOate on the rate of diabetic wound healing. African Journal of Biotechnology. 2014.|[3]Keefer LK, et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms. Methods Enzymol. 1996;268:281-93.
CAS Number
– 146672-58-4
Molecular Weight
– 176.22
Compound Purity
– 98.0
SMILES
– NCCCN(CCC)N(O)N=O
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.