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Pancuronium (dibromide)
$42 – $264
Products Details
Product Description
– Pancuronium dibromide, a bis-quaternary steroid, is a neuromuscular relaxant. Pancuronium dibromide inhibits neuromuscular transmission by competing with acetylcholine for binding sites on nACh receptors. Pancuronium dibromide also inhibits cardiac muscarinic receptors and has a sympathomimetic action[1][2][3].
Web ID
– HY-B0429
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C35H60Br2N2O4
References
– [1]A D Fryer, et al. Pancuronium and gallamine are antagonists for pre- and post-junctional muscarinic receptors in the guinea-pig lung. Naunyn Schmiedebergs Arch Pharmacol. 1987 Apr;335(4):367-71.|[2]E Maestrone, et al. Extracellular pancuronium affects sodium current in chick embryo sensory neurons. Br J Pharmacol. 1994 Jan;111(1):283-7.|[3]J R Docherty, et al. A comparison of the effects of pancuronium bromide and its monoquaternary analogue, ORG NC 45, on autonomic and somatic neurotransmission in the rat. Br J Pharmacol. 1980;71(1):225-33.
CAS Number
– 15500-66-0
Molecular Weight
– 732.67
Compound Purity
– 98.0
SMILES
– C[N+]1([C@@H]2[C@@H](OC(C)=O)C[C@@](CC[C@]3([H])[C@]4([H])CC[C@@]5(C)[C@@]3([H])C[C@H]([N+]6(C)CCCCC6)[C@@H]5OC(C)=O)([H])[C@]4(C)C2)CCCCC1.[Br-].[Br-]
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
