Download Files:
Products Details
Product Description
– Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity[1].
Web ID
– HY-144028
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H18ClF3N6O3
References
– [1]Pan S,et al. Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants. J Med Chem. 2022 Feb 10;65(3):2035-2058.
CAS Number
– 2583778-77-0
Molecular Weight
– 506.86
SMILES
– O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(NC(N=CN=C3N4)=C3OC(C)(C)C4=O)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
