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Pamidronic acid
SKU
HY-B0012-100 mg
Category Reference compound
Tags Anti-infection;Stem Cell/Wnt, Bacterial;Wnt;β-catenin, Cancer; Metabolic Disease; Inflammation/Immunology
$38 – $96
Products Details
Product Description
– Pamidronic acid is a agent used to treat a broad spectrum of bone absorption diseases.
Web ID
– HY-B0012
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C3H11NO7P2
References
– [1]Ashton JA, et al. Investigation of the effect of pamidronate disodium on the in vitro viability of osteosarcoma cellsfrom dogs. Am J Vet Res. 2005 May;66(5):885-91.|[2]Xu Y, et al. Pamidronate Disodium Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells In Vitro. J Oral Maxillofac Surg. 2017 Mar 22.|[3]Lv Y, et al. Effects of pamidronate disodium on the loss of osteoarthritic subchondral bone and the expression of cartilaginous and subchondral osteoprotegerin and RANKL in rabbits. BMC Musculoskelet Disord. 2014 Nov 6;15:370.
CAS Number
– 40391-99-9
Molecular Weight
– 235.07
Compound Purity
– 98.00
SMILES
– OC(P(O)(O)=O)(P(O)(O)=O)CCN
Clinical Information
– Launched
Research Area
– Cancer; Metabolic Disease; Inflammation/Immunology
Solubility
– DMSO : 1 mg/mL (ultrasonic;warming;heat to 80°C)|H2O : 5 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Bacterial;Wnt;β-catenin
Pathway
– Anti-infection;Stem Cell/Wnt
Product type
– Reference compound
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