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PAD-IN-2

$700$5,900

Products Details

Product Description

– PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis[1].

Web ID

– HY-135304

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C27H28ClN5O2

References

– [1]Hallur, Gurulingappa, et al. Heterocyclic compounds as pad4 inhibitors. Patent WO2019058393 A1.

CAS Number

– 2304852-21-7

Molecular Weight

– 490.00

Compound Purity

– 99.02

SMILES

– O=C(N1C[C@H](N)CCC1)C2=CC3=C4N(C(C(N5CC6CC6)=CC7=C5C(Cl)=CC=C7)=N3)CCOC4=C2

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology

Solubility

– DMSO : 70 mg/mL (ultrasonic)

Target

– Protein Arginine Deiminase

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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