Products Details

Product Description

– p38 Kinase inhibitor 5 (AA6) is a potent p38 kinase inhibitor with an IC50 of 403.57 nM. p38 Kinase inhibitor 5 has anti-inflammatory activity[1].

Web ID

– HY-149850

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C23H23F3N4O2

References

– [1]Archana Awasthi, et al. Synthesis, In Silico Studies, and In Vitro Anti-Inflammatory Activity of Novel Imidazole Derivatives Targeting p38 MAP Kinase. ACS Omega. 2023 May 12;8(20):17788-17799.

CAS Number

– 2929285-29-8

Molecular Weight

– 444.45

SMILES

– O=C(NC1=CC=C(C)C=C1C)C(NC(CN2C=C(C(F)(F)F)N=C2)=O)CC3=CC=CC=C3

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– p38 MAPK

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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