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Products Details
Product Description
– p38-α MAPK-IN-4 (Compound 69) is a selective p38α MAPK inhibitor with an IC50 of 1.5 µM. p38-α MAPK-IN-4 rapidly and strongly prevents the development of mechanical allodynia (MA) in vivo[1].
Web ID
– HY-146032
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H13BrN2O
References
– [1]Visseq A, et al. Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia. Eur J Med Chem. 2020 Feb 1;187:111917.
CAS Number
– 2396754-57-5
Molecular Weight
– 341.20
SMILES
– O=C1C(C2=CC=CC=C2Br)=CC(NC3=CC=CC=C3)=CN1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– p38 MAPK
Isoform
– p38α
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
