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Products Details
Product Description
– P-gp inhibitor 3 is an effective P-glycoprotein (P-gp) inhibitor. P-gp inhibitor 3 inhibits the efflux function of P-gp by activating P-gp ATPase. P-gp inhibitor 3 has relatively stronger multidrug resistance (MDR) reversal ability and enhances the anti-tumor activity of Paclitaxel[1].
Web ID
– HY-144366
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C48H67N3O6
References
– [1]Huang W, et al. Design, synthesis, and tumor drug resistance reversal activity of novel hederagenin derivatives modified by nitrogen-containing heterocycles. Eur J Med Chem. 2022;232:114207.
Molecular Weight
– 782.06
SMILES
– CCN1CCN(CC1)C(CCC(OC[C@@]2(C3=C(C[C@]4(C2CC[C@@]5(C4CC=C6C7CC(C)(CC[C@@]7(CC[C@]65C)C(OCC8=CC=CC=C8)=O)C)C)C)C=NO3)C)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– P-glycoprotein
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
