P-gp inhibitor 1

$160$1,350

Products Details

Product Description

– P-gp inhibitor 1 is a novel inhibitor reversing P-glycoprotein-mediated multidrug resistance.

Web ID

– HY-101791

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C32H31N5O2

References

– [1]Qiu Q, et al. Design, Synthesis, and Pharmacological Characterization of N-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance. J Med Chem. 2017 Apr 27;60(8):3289-3302.

CAS Number

– 2050747-49-2

Molecular Weight

– 517.62

Compound Purity

– 98.79

SMILES

– COC(C(OC)=C1)=CC2=C1CCN(C2)CCC3=CC=C(NC4=NC(C5=CC=NC=C5)=NC6=CC=CC=C46)C=C3

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 70°C)

Target

– P-glycoprotein

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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