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OYYF-175
Products Details
Product Description
– OYYF-175, an antimicrobial antifolate, is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.36 nM for Escherichia coli DHFR. OYYF-175 exhibits potent broad-
Web ID
– HY-143408
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H14FN5
References
– [1]Yue Li, et al. The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates. Eur J Med Chem. 2022 Jan 15;228:113979.
CAS Number
– 65829-22-3
Molecular Weight
– 307.32
SMILES
– NC1=C2C3=C(N(CC4=CC=CC=C4F)C=C3)C=CC2=NC(N)=N1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.