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Oxypeucedanin
$202 – $343
Products Details
Product Description
– Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation[1]. Oxypeucedanin induces cell apoptosis through inhibition of cancer cell migration[2].
Web ID
– HY-N0747
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H14O5
References
– [1]Eun JS, et al. Effects of oxypeucedanin on hKv1.5 and action potential duration.Biol Pharm Bull. 2005 Apr;28(4):657-60.|[2]Yu Liu, et al. Oxypeucedanin hydrate monoacetate isolated from Angelica dahurica induces apoptosis in Caco-2 colon carcinoma cells through the mediation of PI3K-signalling pathway and inhibition of cancer cell migration
CAS Number
– 737-52-0
Molecular Weight
– 286.28
Compound Purity
– 98.03
SMILES
– CC1(C)C(O1)COC2=C(C=CO3)C3=CC(O4)=C2C=CC4=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Apoptosis;Potassium Channel
Pathway
– Apoptosis;Membrane Transporter/Ion Channel
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
