Download Files:
Products Details
Product Description
– OX2R-IN-1 (compound 15) is a low cytotoxicity profile OX2R-IN-1 antagonist (a potential OX2R binder) with an IC50 value of 484 μM. OX2R-IN-1 (compound 15) can cross the BBB into the brain with a short half-life[1].
Web ID
– HY-149014
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H28ClN3O5S
References
– [1]Eva Mezeiova, et al. From orexin receptor agonist YNT-185 to novel antagonists with drug-like properties for the treatment of insomnia, Bioorg Chem. 2020 Oct;103:104179.
CAS Number
– 2639148-08-4
Molecular Weight
– 457.97
SMILES
– O=C(C1=CC=C(S(=O)(NC2=CC=CC(CN3CCC(CC3)CO)=C2)=O)N1C)OC.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Orexin Receptor (OX Receptor)
Isoform
– OX2 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
