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Products Details
Product Description
– OSI-296 is a potent, oral and selective inhibitor of cMET and RON kinases. OSI-296 shows in vivo efficacy in MKN45 tumor xenografts models and well tolerated[1].
Web ID
– HY-118269
Shipping
– Room temperature
Molecular Formula
– C21H19Cl2FN4O3
References
– [1]Steinig AG, et al. Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases. Bioorg Med Chem Lett. 2013;23(15):4381-4387.
CAS Number
– 1175296-94-2
Molecular Weight
– 465.30
SMILES
– O=C(N)N1CC=C(CC1)C2=COC3=C2C=NC(N)=C3O[C@H](C)C4=C(C=CC(F)=C4Cl)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Met/HGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
