Products Details

Product Description

– Oseltamivir-d5 is the deuterium labeled Oseltamivir[1]. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50 of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[2].

Web ID

– HY-13317S3

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C16H23D5N2O4

References

– [1]O Ferraris, et al. Sensitivity of Influenza Viruses to Zanamivir and Oseltamivir: A Study Performed on Viruses Circulating in France Prior to the Introduction of Neuraminidase Inhibitors in Clinical Practice. Antiviral Res. 2005 Oct;68(1):43-8.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

CAS Number

– 1093851-63-8

Molecular Weight

– 317.44

SMILES

– CCC(CC)O[C@H]1[C@@H]([C@H](CC(C(OC(C([2H])([2H])[2H])([2H])[2H])=O)=C1)N)NC(C)=O

Clinical Information

– Launched

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Influenza Virus

Pathway

– Anti-infection

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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