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Oncrasin-1
$83 – $571
Products Details
Product Description
– Oncrasin-1 is a highly effective anti-cancer inhibitor that can kill various K-Ras mutant human lung cancer cells at low concentrations.
Web ID
– HY-16662
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H12ClNO
References
– [1]Guo W, et al. Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota. Cancer Res. 2008 Sep 15;68(18):7403-8.|[2]Guo W, et al. Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1). Mol Cancer Ther. 2009 Feb;8(2):441-8.
CAS Number
– 75629-57-1
Molecular Weight
– 269.73
Compound Purity
– 98.28
SMILES
– O=CC1=CN(CC(C=C2)=CC=C2Cl)C3=CC=CC=C31
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Apoptosis;Ras
Pathway
– Apoptosis;GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
