Oncrasin-1

$83$571

Products Details

Product Description

– Oncrasin-1 is a highly effective anti-cancer inhibitor that can kill various K-Ras mutant human lung cancer cells at low concentrations.

Web ID

– HY-16662

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C16H12ClNO

References

– [1]Guo W, et al. Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota. Cancer Res. 2008 Sep 15;68(18):7403-8.|[2]Guo W, et al. Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1). Mol Cancer Ther. 2009 Feb;8(2):441-8.

CAS Number

– 75629-57-1

Molecular Weight

– 269.73

Compound Purity

– 98.28

SMILES

– O=CC1=CN(CC(C=C2)=CC=C2Cl)C3=CC=CC=C31

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Apoptosis;Ras

Pathway

– Apoptosis;GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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