Download Files:
Ombrabulin
$100 – $350
Products Details
Product Description
– Ombrabulin (AVE8062) is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.
Web ID
– HY-14797
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H26N2O6
References
– [1]Kim TJ, et al. Antitumor and antivascular effects of AVE8062 in ovarian carcinoma. Cancer Res. 2007 Oct 1;67(19):9337-45.
CAS Number
– 181816-48-8
Molecular Weight
– 402.44
Compound Purity
– 98.00
SMILES
– O=C(NC1=CC(/C=CC2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC)[C@@H](N)CO
Clinical Information
– Phase 3
Research Area
– Cancer; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
