Products Details

Product Description

– Olinone is a selective BRD4 BrD1 inhibitor[1]. Olinone accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation[2].

Web ID

– HY-100670

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C17H21N3O2

References

– [1]Rodríguez Y, et al. In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4. Proteins. 2020 Mar;88(3):414-430. |[2]Gacias M, et al. Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression. Chem Biol. 2014 Jul 17;21(7):841-854.

CAS Number

– 1770789-37-1

Molecular Weight

– 299.37

SMILES

– CC(NCCCCN1C(CCN2)=C(C2=O)C3=C1C=CC=C3)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Epigenetic Reader Domain

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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