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OICR12694 (TFA)
Products Details
Product Description
– OICR12694 (JNJ-65234637) TFA is an orally active inhibitor of B cell lymphoma 6 (BCL6)[1].
Web ID
– HY-153096A
Shipping
– Room temperature
Molecular Formula
– C29H28ClF3N8O4.xC2HF3O2
References
– [1]Mamai A, et al. Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. ACS Med Chem Lett. 2023 Jan 12;14(2):199-210.
CAS Number
– 2360625-98-3
Molecular Weight
– N/A
SMILES
– O=C1C2=C(N=C3N1CCC3)N(CC(NC4=C(Cl)C(F)=NC(N5[C@H](CN(CC5)C)C)=C4)=O)C=C2C6=CC(C(N)=O)=C(C(F)=C6F)O.O=C(O)C(F)(F)F.[x]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
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