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Products Details
Product Description
– ODN INH-18 sodium is a linear 24-mer class B INH-ODN in which the 5′ INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 sodium showes inhibitory potency for TLR9 ligand-induced IFN-α production.
Web ID
– HY-153840A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
– [1]Lenert P, Yasuda K, Busconi L, et al. DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo. Arthritis Res Ther. 2009;11(3):R79. doi:10.1186/ar2710
Molecular Weight
– N/A
SMILES
– [ODN INH 18 (sodium)]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in H2O
Target
– Toll-like Receptor (TLR)
Pathway
– Immunology/Inflammation
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
