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ODN 24991
$320 – $1,280
Products Details
Product Description
– ODN 24991, a guanine-modified inhibitory oligonucleotide (INH-ODN), is a TLR3, TLR7 and TLR9 (Toll-like receptor) inhibitor, and its parent is INH-ODN 2088. ODN 24991 disrupts TLR3-, TLR7- and TLR9-mediated immune cell immune responses. ODN 24991 sequence: 5′-C-C-T-G-G-C-c7rGm-G-G-G-3′[1].
Web ID
– HY-150746
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
Р[1]Franziska R̦mmler, et al. Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells. PLoS One. 2015 Feb 19;10(2):e0116703.
CAS Number
– 1682661-49-9
Molecular Weight
– N/A
Compound Purity
– 96.0
SMILES
– [DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G)]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– Toll-like Receptor (TLR)
Pathway
– Immunology/Inflammation
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
